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Cognitive impairment without dementia in older people
 — prevalence, vascular risk factors, impact on disability. The Italian Longitudinal Study on Aging
Author(s)Antonio Di Carlo, Marzia Baldereschi, Luigi Amaducci
Journal titleJournal of the American Geriatrics Society, vol 48, no 7, July 2000
Pagespp 775-782
KeywordsCognitive impairment ; At risk ; Dementia ; Mobility ; Self care capacity ; Physical disabilities ; Longitudinal surveys ; Italy.
AnnotationAlthough many studies have evaluated dementing illness prevalence, little information is available on the frequency of and risk factors for cognitive impairment in non-demented (CIND) older people. In this article, study participants were 3425 Italians aged 65-84, living in the community or institutionalised, and screened for cognitive impairment using the Mini-Mental State Examination (MMSE). Trained neurologists examined those scoring <24. CIND diagnosis relied on clinical and neuropsychological examination, informant review, and assessment of functional activities. Age-related cognitive decline (ARCD) was diagnosed in CIND cases without neuropsychiatric disorders responsible for the cognitive impairment. Prevalence was 10.7% for CIND, and 7% for ARCD, increased with age, and was higher in women. Age, stroke and heart failure were significantly and positively associated with CIND at multivariate analysis. Education and smoking showed a negative correlation. Age and myocardial infarction were positively associated with ARCD. CIND occurs very frequently in older people, and the association with functional impairment is useful in evaluating the burden of disability and healthcare demands. (RH).
Accession NumberCPA-000824223 A
ClassmarkE4: CA3: EA: C4: CA: BN: 3J: 76V

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