Centre for Policy on Ageing



Demented patients' participation in a clinical trial — factors affecting the caregivers' decision
Author(s)	P Elad, T A Treves, M Drory
Journal title	International Journal of Geriatric Psychiatry, vol l5, no 4, April 2000
Pages	pp 325-330
Keywords	Dementia ; Drugs ; Informal care ; Participation ; Clinical surveys ; Israel.
Annotation	Clinical trials for Alzheimer's disease (AD) take place in medical centres all over the world. Patients and caregivers have to decide whether or not to agree to participate in clinical trials. This study aimed to investigate the motivation that determines caregivers' choice. 19 caregivers of demented patients who consented to participate in a clinical trial at the authors' memory clinic in Tel Aviv, Israel and 10 caregivers who refused to participate were interviewed. Data were gather by a self-report questionnaire covering various aspects of the caregivers' decision-making process. Among reasons for agreeing to participate in the clinical trial were the respondents' belief that it would improve or help to maintain the patients' condition. Most of the respondents of both groups indicated that information regarding side effects and success probability was adequately provided in advance. The primary reason for refusal was the potential side effects of the drug. (RH).
Accession Number	CPA-000823204 A
Classmark	EA: LLD: P6: TMB: 3G: 7H6
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...from the Ageinfo database published by Centre for Policy on Ageing.