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Delusions and hallucinations in Alzheimer's disease
 — prevalence and clinical correlates
Author(s)Medhat M Bassiony, Martin Steinberg, Andrew Warren
Journal titleInternational Journal of Geriatric Psychiatry, vol 15, no 2, February 2000
Pagespp 99-107
KeywordsDelusion ; Perception disorders ; Dementia ; Correlation ; United States of America.
AnnotationPsychotic symptoms, such as delusions and hallucinations, have been reported in a large proportion of patients with Alzheimer's disease (AD). This American study examines the frequency of both types of symptom (separately and together) in 342 community-dwelling AD patients, and to clarify factors associated with each group. Presence of psychotic symptoms was assessed using DSM-IV glossary definitions. Patients were also rated on standardised measures of cognitive impairment, depression, extrapyramidal symptoms, functional impairment and general health. 75 (22%) had delusions only, 9 (3%) had hallucinations only, and 30 (9%) had both symptoms. Hallucinations were associated with less education, African-American race, more severe dementia, longer duration of illness, falls and use of anxiolytics. Delusions were associated with older age, depression, aggression, poor general health and use of antihypertensives. Those with both symptoms were similar to those with delusions only. The study confirms the high prevalence of psychotic symptoms in AD patients encountered in clinical practice, and suggests that individual psychotic symptoms have different associations. (RH).
Accession NumberCPA-000419013 A
ClassmarkEDD: EE: EA: 49: 7T

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